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Simple biophysics underpins collective conformations of the intrinsically disordered proteins of the Nuclear Pore Complex

Nuclear Pore Complexes (NPCs) are key cellular transporter that control nucleocytoplasmic transport in eukaryotic cells, but its transport mechanism is still not understood. The centerpiece of NPC transport is the assembly of intrinsically disordered polypeptides, known as FG nucleoporins, lining it...

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Detalles Bibliográficos
Autores principales: Vovk, Andrei, Gu, Chad, Opferman, Michael G, Kapinos, Larisa E, Lim, Roderick YH, Coalson, Rob D, Jasnow, David, Zilman, Anton
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4874778/
https://www.ncbi.nlm.nih.gov/pubmed/27198189
http://dx.doi.org/10.7554/eLife.10785