Altered cellular redox status, sirtuin abundance and clock gene expression in a mouse model of developmentally primed NASH()

BACKGROUND: We have previously shown that high fat (HF) feeding during pregnancy primes the development of non-alcoholic steatohepatits (NASH) in the adult offspring. However, the underlying mechanisms are unclear. AIMS: Since the endogenous molecular clock can regulate hepatic lipid metabolism, we...

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Detalles Bibliográficos
Autores principales: Bruce, Kimberley D., Szczepankiewicz, Dawid, Sihota, Kiran K., Ravindraanandan, Manoj, Thomas, Hugh, Lillycrop, Karen A., Burdge, Graham C., Hanson, Mark A., Byrne, Christopher D., Cagampang, Felino R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Pub. Co 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4874946/
https://www.ncbi.nlm.nih.gov/pubmed/27040510
http://dx.doi.org/10.1016/j.bbalip.2016.03.026

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4874946/
https://www.ncbi.nlm.nih.gov/pubmed/27040510
http://dx.doi.org/10.1016/j.bbalip.2016.03.026

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