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Mechanism of inhibiting type I interferon induction by hepatitis B virus X protein
Hepatitis B virus (HBV) is regarded as a stealth virus, invading and replicating efficiently in human liver undetected by host innate antiviral immunity. Here, we show that type I interferon (IFN) induction but not its downstream signaling is blocked by HBV replication in HepG2.2.15 cells. This effe...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Higher Education Press
2011
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4875076/ https://www.ncbi.nlm.nih.gov/pubmed/21213104 http://dx.doi.org/10.1007/s13238-010-0141-8 |