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Mechanism of inhibiting type I interferon induction by hepatitis B virus X protein

Hepatitis B virus (HBV) is regarded as a stealth virus, invading and replicating efficiently in human liver undetected by host innate antiviral immunity. Here, we show that type I interferon (IFN) induction but not its downstream signaling is blocked by HBV replication in HepG2.2.15 cells. This effe...

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Detalles Bibliográficos
Autores principales: Jiang, Junyi, Tang, Hong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Higher Education Press 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4875076/
https://www.ncbi.nlm.nih.gov/pubmed/21213104
http://dx.doi.org/10.1007/s13238-010-0141-8