Liberation of SARS-CoV main protease from the viral polyprotein: N-terminal autocleavage does not depend on the mature dimerization mode

The main protease (M(pro)) plays a vital role in proteolytic processing of the polyproteins in the replicative cycle of SARS coronavirus (SARS-CoV). Dimerization of this enzyme has been shown to be indispensable for transcleavage activity. However, the auto-processing mechanism of M(pro), i.e. its o...

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Detalles Bibliográficos
Autores principales: Chen, Shuai, Jonas, Felix, Shen, Can, Higenfeld, Rolf
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Higher Education Press 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4875104/
https://www.ncbi.nlm.nih.gov/pubmed/21203998
http://dx.doi.org/10.1007/s13238-010-0011-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4875104/
https://www.ncbi.nlm.nih.gov/pubmed/21203998
http://dx.doi.org/10.1007/s13238-010-0011-4

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