Recognition of Lys48-Linked Di-ubiquitin and Deubiquitinating Activities of the SARS Coronavirus Papain-like Protease

Deubiquitinating enzymes (DUBs) recognize and cleave linkage-specific polyubiquitin (polyUb) chains, but mechanisms underlying specificity remain elusive in many cases. The severe acute respiratory syndrome (SARS) coronavirus papain-like protease (PLpro) is a DUB that cleaves ISG15, a two-domain Ub-...

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Detalles Bibliográficos
Autores principales: Békés, Miklós, van der Heden van Noort, Gerbrand J., Ekkebus, Reggy, Ovaa, Huib, Huang, Tony T., Lima, Christopher D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Inc. 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4875570/
https://www.ncbi.nlm.nih.gov/pubmed/27203180
http://dx.doi.org/10.1016/j.molcel.2016.04.016

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4875570/
https://www.ncbi.nlm.nih.gov/pubmed/27203180
http://dx.doi.org/10.1016/j.molcel.2016.04.016

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