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Alteration of matrix metalloproteinase-3 O-glycan structure as a biomarker for disease activity of rheumatoid arthritis

BACKGROUND: Nearly all secreted proteins are glycosylated, and serum glycoproteins that exhibit disease-associated glycosylation changes have potential to be biomarkers. In rheumatoid arthritis (RA), C-reactive protein (CRP), and matrix metalloproteinase-3 (MMP-3) are widely used as serologic biomar...

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Detalles Bibliográficos
Autores principales: Takeshita, Masaru, Kuno, Atsushi, Suzuki, Katsuya, Matsuda, Atsushi, Shimazaki, Hiroko, Nakagawa, Tomomi, Otomo, Yuki, Kabe, Yasuaki, Suematsu, Makoto, Narimatsu, Hisashi, Takeuchi, Tsutomu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4875599/
https://www.ncbi.nlm.nih.gov/pubmed/27209430
http://dx.doi.org/10.1186/s13075-016-1013-2