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Antibodies against Lewis antigens inhibit the binding of human norovirus GII.4 virus-like particles to saliva but not to intestinal Caco-2 cells

BACKGROUND: Human noroviruses (NoVs) are the main cause of gastroenteritis worldwide. The most commonly detected NoV strains belong to the genetically diverse GII.4 genotype, with new pandemic variants emerging periodically. Despite extensive efforts, NoV investigation has been hampered by the lack...

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Detalles Bibliográficos
Autores principales: Carmona-Vicente, Noelia, Allen, David J., Rodríguez-Díaz, Jesús, Iturriza-Gómara, Miren, Buesa, Javier
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4875664/
https://www.ncbi.nlm.nih.gov/pubmed/27206610
http://dx.doi.org/10.1186/s12985-016-0538-y