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Identification and characterization of the novel nuclease activity of human phospholipid scramblase 1

BACKGROUND: Human phospholipid scramblase 1 (hPLSCR1) was initially identified as a Ca(2+) dependent phospholipid translocator involved in disrupting membrane asymmetry. Recent reports revealed that hPLSCR1 acts as a multifunctional signaling molecule rather than functioning as scramblase. hPLSCR1 i...

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Detalles Bibliográficos
Autores principales: Sivagnanam, Ulaganathan, Narayana Murthy, Shweta, Gummadi, Sathyanarayana N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4875679/
https://www.ncbi.nlm.nih.gov/pubmed/27206388
http://dx.doi.org/10.1186/s12858-016-0067-8