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Identification and characterization of the novel nuclease activity of human phospholipid scramblase 1
BACKGROUND: Human phospholipid scramblase 1 (hPLSCR1) was initially identified as a Ca(2+) dependent phospholipid translocator involved in disrupting membrane asymmetry. Recent reports revealed that hPLSCR1 acts as a multifunctional signaling molecule rather than functioning as scramblase. hPLSCR1 i...
Autores principales: | Sivagnanam, Ulaganathan, Narayana Murthy, Shweta, Gummadi, Sathyanarayana N. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4875679/ https://www.ncbi.nlm.nih.gov/pubmed/27206388 http://dx.doi.org/10.1186/s12858-016-0067-8 |
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