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Hippo/YAP signaling pathway is involved in osteosarcoma chemoresistance
BACKGROUND: Osteosarcoma is the most common bone malignancy in children and adolescents, and 20%–30% of the patients suffer from poor prognosis because of individual chemoresistance. The Hippo/yes-associated protein (YAP) signaling pathway has been shown to play a role in tumor chemoresistance, but...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4875723/ https://www.ncbi.nlm.nih.gov/pubmed/27206784 http://dx.doi.org/10.1186/s40880-016-0109-z |