Cargando…

The Apoe(−/−) mouse model: a suitable model to study cardiovascular and respiratory diseases in the context of cigarette smoke exposure and harm reduction

Atherosclerosis-prone apolipoprotein E-deficient (Apoe(−/−)) mice display poor lipoprotein clearance with subsequent accumulation of cholesterol ester-enriched particles in the blood, which promote the development of atherosclerotic plaques. Therefore, the Apoe(−/−) mouse model is well established f...

Descripción completa

Detalles Bibliográficos
Autores principales: Lo Sasso, Giuseppe, Schlage, Walter K., Boué, Stéphanie, Veljkovic, Emilija, Peitsch, Manuel C., Hoeng, Julia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4875735/
https://www.ncbi.nlm.nih.gov/pubmed/27207171
http://dx.doi.org/10.1186/s12967-016-0901-1