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Cytotoxicity of Oxycodone and Morphine in Human Neuroblastoma and Mouse Motoneuronal Cells: A Comparative Approach

BACKGROUND AND OBJECTIVES: Oxycodone is the mo st commonly used opioid for the treatment of moderate to severe pain. The peak cerebrospinal fluid concentration after epidural oxycodone was reported to be 300-fold greater (0.025 mM) than when administered intravenously after gynecologic surgery. Addi...

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Detalles Bibliográficos
Autores principales: Kokki, Merja, Pesonen, Maija, Vehviläinen, Piia, Litmala, Outi, Pasanen, Markku, Kokki, Hannu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4875920/
https://www.ncbi.nlm.nih.gov/pubmed/26913723
http://dx.doi.org/10.1007/s40268-016-0125-0