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Cytotoxicity of Oxycodone and Morphine in Human Neuroblastoma and Mouse Motoneuronal Cells: A Comparative Approach
BACKGROUND AND OBJECTIVES: Oxycodone is the mo st commonly used opioid for the treatment of moderate to severe pain. The peak cerebrospinal fluid concentration after epidural oxycodone was reported to be 300-fold greater (0.025 mM) than when administered intravenously after gynecologic surgery. Addi...
Autores principales: | Kokki, Merja, Pesonen, Maija, Vehviläinen, Piia, Litmala, Outi, Pasanen, Markku, Kokki, Hannu |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer International Publishing
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4875920/ https://www.ncbi.nlm.nih.gov/pubmed/26913723 http://dx.doi.org/10.1007/s40268-016-0125-0 |
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