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Improving isopropanol tolerance and production of Clostridium beijerinckii DSM 6423 by random mutagenesis and genome shuffling

Random mutagenesis and genome shuffling was applied to improve solvent tolerance and isopropanol/butanol/ethanol (IBE) production in the strictly anaerobic bacteria Clostridium beijerinckii DSM 6423. Following chemical mutagenesis with N-methyl-N-nitro-N-nitrosoguanidine (NTG), screening of putative...

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Detalles Bibliográficos
Autores principales: Gérando, H. Máté de, Fayolle-Guichard, F., Rudant, L., Millah, S. K., Monot, F., Ferreira, Nicolas Lopes, López-Contreras, A. M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4875934/
https://www.ncbi.nlm.nih.gov/pubmed/26852409
http://dx.doi.org/10.1007/s00253-016-7302-5