Pharmacokinetics and Pharmacodynamics of Edoxaban, a Non-Vitamin K Antagonist Oral Anticoagulant that Inhibits Clotting Factor Xa

Edoxaban, a once daily non-vitamin K antagonist oral anticoagulant, is a direct, selective, reversible inhibitor of factor Xa (FXa). In healthy subjects, single oral doses of edoxaban result in peak plasma concentrations within 1.0–2.0 h of administration, followed by a biphasic decline. Exposure is...

Descripción completa

Detalles Bibliográficos
Autores principales: Parasrampuria, Dolly A., Truitt, Kenneth E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2015
Materias:
Review Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4875962/
https://www.ncbi.nlm.nih.gov/pubmed/26620048
http://dx.doi.org/10.1007/s40262-015-0342-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4875962/
https://www.ncbi.nlm.nih.gov/pubmed/26620048
http://dx.doi.org/10.1007/s40262-015-0342-7

Ejemplares similares