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(Z)-5-(2,4-Dihydroxybenzylidene)thiazolidine-2,4-dione Prevents UVB-Induced Melanogenesis and Wrinkle Formation through Suppressing Oxidative Stress in HRM-2 Hairless Mice

Background. Uncontrolled melanogenesis and wrinkle formation are an indication of photoaging. Our previous studies demonstrated that (Z)-5-(2,4-dihydroxybenzylidene)thiazolidine-2,4-dione (MHY498) inhibited tyrosinase activity and melanogenesis in vitro. Objective. To examine in vivo effects of MHY4...

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Detalles Bibliográficos
Autores principales: Lee, Bonggi, Moon, Kyoung Mi, Kim, Seong Jin, Kim, So Hee, Kim, Dae Hyun, An, Hye Jin, Jeong, Ji Won, Kim, Ye Ra, Son, Sujin, Kim, Min Jo, Chung, Ki Wung, Lee, Eun Kyeong, Chun, Pusoon, Ha, Young Mi, Kim, Min-Sun, Mo, Sang Hyun, Moon, Hyung Ryong, Chung, Hae Young
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4875997/
https://www.ncbi.nlm.nih.gov/pubmed/27242917
http://dx.doi.org/10.1155/2016/2761463