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Clinical efficacy of perampanel for partial-onset and primary generalized tonic–clonic seizures
BACKGROUND AND PURPOSE: Perampanel, a selective noncompetitive antagonist at the α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) receptor, is highly effective in a wide range of experimental models. Although initially licensed as adjunctive therapy for partial seizures with or without se...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Dove Medical Press
2016
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4876101/ https://www.ncbi.nlm.nih.gov/pubmed/27274257 http://dx.doi.org/10.2147/NDT.S83842 |