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LRRK2 Regulates Voltage-Gated Calcium Channel Function

Voltage-gated Ca(2+) (Ca(V)) channels enable Ca(2+) influx in response to membrane depolarization. Ca(V)2.1 channels are localized to the presynaptic membrane of many types of neurons where they are involved in triggering neurotransmitter release. Several signaling proteins have been identified as i...

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Detalles Bibliográficos
Autores principales: Bedford, Cade, Sears, Catherine, Perez-Carrion, Maria, Piccoli, Giovanni, Condliffe, Steven B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4876133/
https://www.ncbi.nlm.nih.gov/pubmed/27242426
http://dx.doi.org/10.3389/fnmol.2016.00035