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Benzolamide improves oxygenation and reduces acute mountain sickness during a high‐altitude trek and has fewer side effects than acetazolamide at sea level

Acetazolamide is the standard carbonic anhydrase (CA) inhibitor used for acute mountain sickness (AMS), however some of its undesirable effects are related to intracellular penetrance into many tissues, including across the blood–brain barrier. Benzolamide is a much more hydrophilic inhibitor, which...

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Detalles Bibliográficos
Autores principales: Collier, David J., Wolff, Chris B., Hedges, Anne‐Marie, Nathan, John, Flower, Rod J., Milledge, James S., Swenson, Erik R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4876137/
https://www.ncbi.nlm.nih.gov/pubmed/27433337
http://dx.doi.org/10.1002/prp2.203