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Benzolamide improves oxygenation and reduces acute mountain sickness during a high‐altitude trek and has fewer side effects than acetazolamide at sea level
Acetazolamide is the standard carbonic anhydrase (CA) inhibitor used for acute mountain sickness (AMS), however some of its undesirable effects are related to intracellular penetrance into many tissues, including across the blood–brain barrier. Benzolamide is a much more hydrophilic inhibitor, which...
Autores principales: | Collier, David J., Wolff, Chris B., Hedges, Anne‐Marie, Nathan, John, Flower, Rod J., Milledge, James S., Swenson, Erik R. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4876137/ https://www.ncbi.nlm.nih.gov/pubmed/27433337 http://dx.doi.org/10.1002/prp2.203 |
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