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Snapshot of the prescribing practice for the clopidogrel and esomeprazole coprescription and cost evaluation of the application guidelines

The antiplatelet clopidogrel and the proton pump inhibitor esomeprazole demonstrate a pharmacokinetic interaction through CYP2C19 that could translate into clinical inefficacy of clopidogrel. No medical consensus as to their coprescription has been reached, and different guidelines are available. We...

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Detalles Bibliográficos
Autores principales: Vernaz, Nathalie, Rollason, Victoria, Adlere, Liene, Combescure, Christophe, Poncet, Antoine, Bonnabry, Pascal, Desmeules, Jules
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4876144/
https://www.ncbi.nlm.nih.gov/pubmed/27433344
http://dx.doi.org/10.1002/prp2.234