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Genistein upregulates LDLR levels via JNK-mediated activation of SREBP-2
BACKGROUND: Genistein has been proved in vitro and in vivo to lower LDLR level. It is also widely consumed and implicated for its anti-atherogenic effects. However, the molecular mechanism by which genistein lowers the LDL level is still unknown. OBJECTIVE: To understand the anti-atherogenic molecul...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Co-Action Publishing
2016
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4876195/ https://www.ncbi.nlm.nih.gov/pubmed/27211318 http://dx.doi.org/10.3402/fnr.v60.31120 |