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Genistein upregulates LDLR levels via JNK-mediated activation of SREBP-2

BACKGROUND: Genistein has been proved in vitro and in vivo to lower LDLR level. It is also widely consumed and implicated for its anti-atherogenic effects. However, the molecular mechanism by which genistein lowers the LDL level is still unknown. OBJECTIVE: To understand the anti-atherogenic molecul...

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Detalles Bibliográficos
Autores principales:	Kartawijaya, Medicia, Han, Hye Won, Kim, Yunhye, Lee, Seung-Min
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Co-Action Publishing 2016
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4876195/ https://www.ncbi.nlm.nih.gov/pubmed/27211318 http://dx.doi.org/10.3402/fnr.v60.31120

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