Honokiol suppresses TNF-α-induced neutrophil adhesion on cerebral endothelial cells by disrupting polyubiquitination and degradation of IκBα

Adhesion molecules expressed on cerebral endothelial cells (ECs) mediate leukocyte recruitment and play a significant role in cerebral inflammation. Increased levels of adhesion molecules on the EC surface induce leukocyte infiltration into inflammatory areas and are thus hallmarkers of inflammation...

Descripción completa

Detalles Bibliográficos
Autores principales: Chen, Po-Jen, Wang, Yu-Ling, Kuo, Liang-Mou, Lin, Chwan-Fwu, Chen, Chun-Yu, Tsai, Yung-Fong, Shen, Jiann-Jong, Hwang, Tsong-Long
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4876378/
https://www.ncbi.nlm.nih.gov/pubmed/27212040
http://dx.doi.org/10.1038/srep26554

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4876378/
https://www.ncbi.nlm.nih.gov/pubmed/27212040
http://dx.doi.org/10.1038/srep26554

Ejemplares similares