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Honokiol suppresses TNF-α-induced neutrophil adhesion on cerebral endothelial cells by disrupting polyubiquitination and degradation of IκBα

Adhesion molecules expressed on cerebral endothelial cells (ECs) mediate leukocyte recruitment and play a significant role in cerebral inflammation. Increased levels of adhesion molecules on the EC surface induce leukocyte infiltration into inflammatory areas and are thus hallmarkers of inflammation...

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Detalles Bibliográficos
Autores principales:	Chen, Po-Jen, Wang, Yu-Ling, Kuo, Liang-Mou, Lin, Chwan-Fwu, Chen, Chun-Yu, Tsai, Yung-Fong, Shen, Jiann-Jong, Hwang, Tsong-Long
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2016
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4876378/ https://www.ncbi.nlm.nih.gov/pubmed/27212040 http://dx.doi.org/10.1038/srep26554

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