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Suppression of 14-3-3γ-mediated surface expression of ANO1 inhibits cancer progression of glioblastoma cells

Anoctamin-1 (ANO1) acts as a Ca(2+)-activated Cl(−) channel in various normal tissues, and its expression is increased in several different types of cancer. Therefore, understanding the regulation of ANO1 surface expression is important for determining its physiological and pathophysiological functi...

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Detalles Bibliográficos
Autores principales: Lee, Young-Sun, Lee, Jae Kwang, Bae, Yeonju, Lee, Bok-Soon, Kim, Eunju, Cho, Chang-Hoon, Ryoo, Kanghyun, Yoo, Jiyun, Kim, Chul-Ho, Yi, Gwan-Su, Lee, Seok-Geun, Lee, C. Justin, Kang, Sang Soo, Hwang, Eun Mi, Park, Jae-Yong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4876403/
https://www.ncbi.nlm.nih.gov/pubmed/27212225
http://dx.doi.org/10.1038/srep26413