Estimating the sample size for a pilot randomised trial to minimise the overall trial sample size for the external pilot and main trial for a continuous outcome variable

Sample size justification is an important consideration when planning a clinical trial, not only for the main trial but also for any preliminary pilot trial. When the outcome is a continuous variable, the sample size calculation requires an accurate estimate of the standard deviation of the outcome...

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Detalles Bibliográficos
Autores principales: Whitehead, Amy L, Julious, Steven A, Cooper, Cindy L, Campbell, Michael J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2015
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4876429/
https://www.ncbi.nlm.nih.gov/pubmed/26092476
http://dx.doi.org/10.1177/0962280215588241

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4876429/
https://www.ncbi.nlm.nih.gov/pubmed/26092476
http://dx.doi.org/10.1177/0962280215588241

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