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Novel application of hydrophobin in medical science: a drug carrier for improving serum stability

Multiple physiological properties of glucagon-like peptide-1 (GLP-1) ensure that it is a promising drug candidate for the treatment of type 2 diabetes. However, the in vivo half-life of GLP-1 is short because of rapid degradation by dipeptidyl peptidase-IV (DPP-IV) and renal clearance. The poor seru...

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Detalles Bibliográficos
Autores principales: Zhao, Liqiang, Xu, Haijin, Li, Ying, Song, Dongmin, Wang, Xiangxiang, Qiao, Mingqiang, Gong, Min
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4876437/
https://www.ncbi.nlm.nih.gov/pubmed/27212208
http://dx.doi.org/10.1038/srep26461