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Raised HIF1α during normoxia in high altitude pulmonary edema susceptible non-mountaineers

High altitude pulmonary edema (HAPE) susceptibility is associated with EGLN1 polymorphisms, we hypothesized that HAPE-susceptible (HAPE-S, had HAPE episode in past) subjects may exhibit abnormal HIF1α levels in normoxic conditions. We measured HIF1α levels in HAPE-S and HAPE resistant (HAPE-R, no HA...

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Detalles Bibliográficos
Autores principales: Soree, Poonam, Gupta, Rajinder K., Singh, Krishan, Desiraju, Koundinya, Agrawal, Anurag, Vats, Praveen, Bharadwaj, Abhishek, Baburaj, T. P., Chaudhary, Pooja, Singh, Vijay K., Verma, Saroj, Bajaj, Amir Chand, Singh, Shashi Bala
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4876441/
https://www.ncbi.nlm.nih.gov/pubmed/27210110
http://dx.doi.org/10.1038/srep26468