Gut environment-induced intraepithelial autoreactive CD4(+) T cells suppress central nervous system autoimmunity via LAG-3

The gut environment has been found to significantly influence autoimmune diseases such as multiple sclerosis; however, immune cell mechanisms are unclear. Here we show that the gut epithelium of myelin oligodendrocyte glycoprotein(35-55)-specific T-cell receptor transgenic mice contains environmenta...

Descripción completa

Detalles Bibliográficos
Autores principales: Kadowaki, Atsushi, Miyake, Sachiko, Saga, Ryoko, Chiba, Asako, Mochizuki, Hideki, Yamamura, Takashi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4876462/
https://www.ncbi.nlm.nih.gov/pubmed/27198196
http://dx.doi.org/10.1038/ncomms11639

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4876462/
https://www.ncbi.nlm.nih.gov/pubmed/27198196
http://dx.doi.org/10.1038/ncomms11639

Ejemplares similares