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Gut environment-induced intraepithelial autoreactive CD4(+) T cells suppress central nervous system autoimmunity via LAG-3

The gut environment has been found to significantly influence autoimmune diseases such as multiple sclerosis; however, immune cell mechanisms are unclear. Here we show that the gut epithelium of myelin oligodendrocyte glycoprotein(35-55)-specific T-cell receptor transgenic mice contains environmenta...

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Detalles Bibliográficos
Autores principales:	Kadowaki, Atsushi, Miyake, Sachiko, Saga, Ryoko, Chiba, Asako, Mochizuki, Hideki, Yamamura, Takashi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2016
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4876462/ https://www.ncbi.nlm.nih.gov/pubmed/27198196 http://dx.doi.org/10.1038/ncomms11639

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