Proline-rich tyrosine kinase 2 via enhancing signal transducer and activator of transcription 3-dependent cJun expression mediates retinal neovascularization

Despite the involvement of proline-rich tyrosine kinase 2 (Pyk2) in endothelial cell angiogenic responses, its role in pathological retinal angiogenesis is not known. In the present study, we show that vascular endothelial growth factor A (VEGFA) induces Pyk2 activation in mediating human retinal mi...

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Detalles Bibliográficos
Autores principales: Kumar, Raj, Singh, Nikhlesh K., Rao, Gadiparthi N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4876476/
https://www.ncbi.nlm.nih.gov/pubmed/27210483
http://dx.doi.org/10.1038/srep26480

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4876476/
https://www.ncbi.nlm.nih.gov/pubmed/27210483
http://dx.doi.org/10.1038/srep26480

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