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Proline-rich tyrosine kinase 2 via enhancing signal transducer and activator of transcription 3-dependent cJun expression mediates retinal neovascularization

Despite the involvement of proline-rich tyrosine kinase 2 (Pyk2) in endothelial cell angiogenic responses, its role in pathological retinal angiogenesis is not known. In the present study, we show that vascular endothelial growth factor A (VEGFA) induces Pyk2 activation in mediating human retinal mi...

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Detalles Bibliográficos
Autores principales:	Kumar, Raj, Singh, Nikhlesh K., Rao, Gadiparthi N.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2016
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4876476/ https://www.ncbi.nlm.nih.gov/pubmed/27210483 http://dx.doi.org/10.1038/srep26480

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