Finding novel distinctions between the sAPPα-mediated anabolic biochemical pathways in Autism Spectrum Disorder and Fragile X Syndrome plasma and brain tissue

Autism spectrum disorder (ASD) and Fragile X syndrome (FXS) are developmental disorders. No validated blood-based biomarkers exist for either, which impedes bench-to-bedside approaches. Amyloid-β (Aβ) precursor protein (APP) and metabolites are usually associated with Alzheimer’s disease (AD). APP c...

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Detalles Bibliográficos
Autores principales: Ray, Balmiki, Sokol, Deborah K., Maloney, Bryan, Lahiri, Debomoy K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4876513/
https://www.ncbi.nlm.nih.gov/pubmed/27212113
http://dx.doi.org/10.1038/srep26052

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4876513/
https://www.ncbi.nlm.nih.gov/pubmed/27212113
http://dx.doi.org/10.1038/srep26052

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