Brief Report: HIV-1 Evolution in Breakthrough Infections in a Human Trial of Oral Pre-exposure Prophylaxis With Emtricitabine and Tenofovir Disoproxil Fumarate

We describe HIV-1 evolutionary dynamics in the 4 participants from the TDF2-PrEP trial who became HIV-1 infected while prescribed emtricitabine and tenofovir disoproxil fumarate (FTC/TDF). At seroconversion, virus diversity in the 2 participants with detectable drug was only 0.05% (95% confidence in...

Descripción completa

Detalles Bibliográficos
Autores principales: Ruone, Susan, Paxton, Lynn, McLaurin, Tony, Taylor, Allan, Hanson, Debra, Heneine, Walid, Brooks, John T., García-Lerma, José Gerardo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: JAIDS Journal of Acquired Immune Deficiency Syndromes 2016
Materias:
Basic and Translational Science
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4876572/
https://www.ncbi.nlm.nih.gov/pubmed/26689970
http://dx.doi.org/10.1097/QAI.0000000000000921

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4876572/
https://www.ncbi.nlm.nih.gov/pubmed/26689970
http://dx.doi.org/10.1097/QAI.0000000000000921

Ejemplares similares