Supramolecular Crafting of Self-Assembling Camptothecin Prodrugs with Enhanced Efficacy against Primary Cancer Cells

Chemical modification of small molecule hydrophobic drugs is a clinically proven strategy to devise prodrugs with enhanced treatment efficacy. While this prodrug strategy improves the parent drug's water solubility and pharmacokinetic profile, it typically compromises the drug's potency ag...

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Detalles Bibliográficos
Autores principales: Su, Hao, Zhang, Pengcheng, Cheetham, Andrew G, Koo, Jin Mo, Lin, Ran, Masood, Asad, Schiapparelli, Paula, Quiñones-Hinojosa, Alfredo, Cui, Honggang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4876630/
https://www.ncbi.nlm.nih.gov/pubmed/27217839
http://dx.doi.org/10.7150/thno.15420

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4876630/
https://www.ncbi.nlm.nih.gov/pubmed/27217839
http://dx.doi.org/10.7150/thno.15420

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