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(111)In-exendin Uptake in the Pancreas Correlates With the β-Cell Mass and Not With the α-Cell Mass
Targeting of the GLP-1 receptor with (111)In-labeled exendin is an attractive approach to determine the β-cell mass (BCM). Preclinical studies as well as a proof-of-concept study in type 1 diabetic patients and healthy subjects showed a direct correlation between BCM and radiotracer uptake. Despite...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American Diabetes Association
2015
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4876689/ https://www.ncbi.nlm.nih.gov/pubmed/25409700 http://dx.doi.org/10.2337/db14-1212 |