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(111)In-exendin Uptake in the Pancreas Correlates With the β-Cell Mass and Not With the α-Cell Mass

Targeting of the GLP-1 receptor with (111)In-labeled exendin is an attractive approach to determine the β-cell mass (BCM). Preclinical studies as well as a proof-of-concept study in type 1 diabetic patients and healthy subjects showed a direct correlation between BCM and radiotracer uptake. Despite...

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Detalles Bibliográficos
Autores principales:	Brom, Maarten, Joosten, Lieke, Frielink, Cathelijne, Boerman, Otto, Gotthardt, Martin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Diabetes Association 2015
Materias:	Islet Studies
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4876689/ https://www.ncbi.nlm.nih.gov/pubmed/25409700 http://dx.doi.org/10.2337/db14-1212

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