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PCSK7 Genotype Modifies Effect of a Weight-Loss Diet on 2-Year Changes of Insulin Resistance: The POUNDS LOST Trial

OBJECTIVE: A common variant rs236918 in the PCSK7 gene has the strongest association with iron homeostasis and is related to insulin resistance. Dietary carbohydrate (CHO) modulates the genetic effect on insulin resistance. We examined whether 2-year weight-loss diets modify the effect of PCSK7 gene...

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Detalles Bibliográficos
Autores principales: Huang, Tao, Huang, Jinyan, Qi, Qibin, Li, Yanping, Bray, George A., Rood, Jennifer, Sacks, Frank M., Qi, Lu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Diabetes Association 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4876697/
https://www.ncbi.nlm.nih.gov/pubmed/25504030
http://dx.doi.org/10.2337/dc14-0473