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Leptin Suppresses Mouse Taste Cell Responses to Sweet Compounds

Leptin is known to selectively suppress neural and behavioral responses to sweet-tasting compounds. However, the molecular basis for the effect of leptin on sweet taste is not known. Here, we report that leptin suppresses sweet taste via leptin receptors (Ob-Rb) and K(ATP) channels expressed selecti...

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Detalles Bibliográficos
Autores principales: Yoshida, Ryusuke, Noguchi, Kenshi, Shigemura, Noriatsu, Jyotaki, Masafumi, Takahashi, Ichiro, Margolskee, Robert F., Ninomiya, Yuzo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Diabetes Association 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4876703/
https://www.ncbi.nlm.nih.gov/pubmed/26116698
http://dx.doi.org/10.2337/db14-1462