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miR-92a Corrects CD34(+) Cell Dysfunction in Diabetes by Modulating Core Circadian Genes Involved in Progenitor Differentiation

Autologous CD34(+) cells are widely used for vascular repair; however, in individuals with diabetes and microvascular disease these cells are dysfunctional. In this study, we examine expression of the clock genes Clock, Bmal, Per1, Per2, Cry1, and Cry2 in CD34(+) cells of diabetic and nondiabetic or...

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Detalles Bibliográficos
Autores principales: Bhatwadekar, Ashay D., Yan, Yuanqing, Stepps, Valerie, Hazra, Sugata, Korah, Maria, Bartelmez, Stephen, Chaqour, Brahim, Grant, Maria B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Diabetes Association 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4876760/
https://www.ncbi.nlm.nih.gov/pubmed/26283734
http://dx.doi.org/10.2337/db15-0521