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The microRNA-29 Family Dictates the Balance Between Homeostatic and Pathological Glucose Handling in Diabetes and Obesity

The microRNA-29 (miR-29) family is among the most abundantly expressed microRNA in the pancreas and liver. Here, we investigated the function of miR-29 in glucose regulation using miR-29a/b-1 (miR-29a)-deficient mice and newly generated miR-29b-2/c (miR-29c)-deficient mice. We observed multiple inde...

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Detalles Bibliográficos
Autores principales: Dooley, James, Garcia-Perez, Josselyn E., Sreenivasan, Jayasree, Schlenner, Susan M., Vangoitsenhoven, Roman, Papadopoulou, Aikaterini S., Tian, Lei, Schonefeldt, Susann, Serneels, Lutgarde, Deroose, Christophe, Staats, Kim A., Van der Schueren, Bart, De Strooper, Bart, McGuinness, Owen P., Mathieu, Chantal, Liston, Adrian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Diabetes Association 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4876765/
https://www.ncbi.nlm.nih.gov/pubmed/26696639
http://dx.doi.org/10.2337/db15-0770