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Ursolic acid reduces the metalloprotease/anti-metalloprotease imbalance in cerebral ischemia and reperfusion injury

BACKGROUND: Activators of PPARs, particularly PPARγ, may be effective neuroprotective drugs against inflammatory responses in cerebral ischemia and reperfusion injury. Ursolic acid (UA) may act as a PPARγ agonist and serve as an anti-inflammatory agent. In this study, we used a rat middle cerebral a...

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Detalles Bibliográficos
Autores principales: Wang, Yanzhe, He, Zhiyi, Deng, Shumin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4876798/
https://www.ncbi.nlm.nih.gov/pubmed/27274199
http://dx.doi.org/10.2147/DDDT.S103829