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Effect of the IL-1 Receptor Antagonist Kineret(®) on Disease Phenotype in mdx Mice

Duchenne muscular dystrophy (DMD) is an X-linked muscle disease caused by mutations in the dystrophin gene. The pathology of DMD manifests in patients with progressive muscle weakness, loss of ambulation and ultimately death. One of the characteristics of DMD is muscle inflammation, and dystrophin-d...

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Detalles Bibliográficos
Autores principales: Benny Klimek, Margaret E., Sali, Arpana, Rayavarapu, Sree, Van der Meulen, Jack H., Nagaraju, Kanneboyina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4877010/
https://www.ncbi.nlm.nih.gov/pubmed/27213537
http://dx.doi.org/10.1371/journal.pone.0155944