Cargando…
Effect of the IL-1 Receptor Antagonist Kineret(®) on Disease Phenotype in mdx Mice
Duchenne muscular dystrophy (DMD) is an X-linked muscle disease caused by mutations in the dystrophin gene. The pathology of DMD manifests in patients with progressive muscle weakness, loss of ambulation and ultimately death. One of the characteristics of DMD is muscle inflammation, and dystrophin-d...
Autores principales: | Benny Klimek, Margaret E., Sali, Arpana, Rayavarapu, Sree, Van der Meulen, Jack H., Nagaraju, Kanneboyina |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2016
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4877010/ https://www.ncbi.nlm.nih.gov/pubmed/27213537 http://dx.doi.org/10.1371/journal.pone.0155944 |
Ejemplares similares
-
The Proton Pump Inhibitor Lansoprazole Improves the Skeletal Phenotype in Dystrophin Deficient mdx Mice
por: Sali, Arpana, et al.
Publicado: (2013) -
Characterization of Dysferlin Deficient SJL/J Mice to Assess Preclinical Drug Efficacy: Fasudil Exacerbates Muscle Disease Phenotype
por: Rayavarapu, Sree, et al.
Publicado: (2010) -
IL-6 signaling blockade increases inflammation but does not affect muscle function in the mdx mouse
por: Kostek, Matthew C, et al.
Publicado: (2012) -
Daily Supplementation of D-ribose Shows No Therapeutic Benefits in the MHC-I Transgenic Mouse Model of Inflammatory Myositis
por: Coley, William, et al.
Publicado: (2013) -
Glucocorticoid-Treated Mice Are an Inappropriate Positive Control for Long-Term Preclinical Studies in the mdx Mouse
por: Sali, Arpana, et al.
Publicado: (2012)