Inhibition of Cardiac Kir Current (I(K1)) by Protein Kinase C Critically Depends on PKCβ and Kir2.2

BACKGROUND: Cardiac inwardly rectifying Kir current (I(K1)) mediates terminal repolarisation and is critical for the stabilization of the diastolic membrane potential. Its predominant molecular basis in mammalian ventricle is heterotetrameric assembly of Kir2.1 and Kir2.2 channel subunits. It has be...

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Detalles Bibliográficos
Autores principales: Scherer, Daniel, Seyler, Claudia, Xynogalos, Panagiotis, Scholz, Eberhard P., Thomas, Dierk, Backs, Johannes, Andrassy, Martin, Völkers, Mirko, Karle, Christoph A., Katus, Hugo A., Zitron, Edgar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4877014/
https://www.ncbi.nlm.nih.gov/pubmed/27214373
http://dx.doi.org/10.1371/journal.pone.0156181

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4877014/
https://www.ncbi.nlm.nih.gov/pubmed/27214373
http://dx.doi.org/10.1371/journal.pone.0156181

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