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Early Transcriptional Signatures of the Immune Response to a Live Attenuated Tetravalent Dengue Vaccine Candidate in Non-human Primates

BACKGROUND: The development of a vaccine against dengue faces unique challenges, including the complexity of the immune responses to the four antigenically distinct serotypes. Genome-wide transcriptional profiling provides insight into the pathways and molecular features that underlie responses to i...

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Detalles Bibliográficos
Autores principales: Strouts, Fiona R., Popper, Stephen J., Partidos, Charalambos D., Stinchcomb, Dan T., Osorio, Jorge E., Relman, David A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4877054/
https://www.ncbi.nlm.nih.gov/pubmed/27214236
http://dx.doi.org/10.1371/journal.pntd.0004731