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Early Transcriptional Signatures of the Immune Response to a Live Attenuated Tetravalent Dengue Vaccine Candidate in Non-human Primates
BACKGROUND: The development of a vaccine against dengue faces unique challenges, including the complexity of the immune responses to the four antigenically distinct serotypes. Genome-wide transcriptional profiling provides insight into the pathways and molecular features that underlie responses to i...
Autores principales: | Strouts, Fiona R., Popper, Stephen J., Partidos, Charalambos D., Stinchcomb, Dan T., Osorio, Jorge E., Relman, David A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4877054/ https://www.ncbi.nlm.nih.gov/pubmed/27214236 http://dx.doi.org/10.1371/journal.pntd.0004731 |
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