Mouse and Human CD1d-Self-Lipid Complexes Are Recognized Differently by Murine Invariant Natural Killer T Cell Receptors

Invariant natural killer T (iNKT) cells recognize self-lipids presented by CD1d through characteristic TCRs, which mainly consist of the invariant Vα14-Jα18 TCRα chain and Vβ8.2, 7 or 2 TCRβ chains with hypervariable CDR3β sequences in mice. The iNKT cell-CD1d axis is conserved between humans and mi...

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Detalles Bibliográficos
Autores principales: Guo, Tingxi, Chamoto, Kenji, Nakatsugawa, Munehide, Ochi, Toshiki, Yamashita, Yuki, Anczurowski, Mark, Butler, Marcus O., Hirano, Naoto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4877060/
https://www.ncbi.nlm.nih.gov/pubmed/27213277
http://dx.doi.org/10.1371/journal.pone.0156114

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4877060/
https://www.ncbi.nlm.nih.gov/pubmed/27213277
http://dx.doi.org/10.1371/journal.pone.0156114

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