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Imposed Optical Defocus Induces Isoform-Specific Up-Regulation of TGFβ Gene Expression in Chick Retinal Pigment Epithelium and Choroid but Not Neural Retina

PURPOSE: This study investigated the gene expression of TGFβ isoforms and their receptors in chick retina, retinal pigment epithelium (RPE), and choroid and the effects of short-term imposed optical defocus. METHODS: The expression of TGFβ isoforms (TGF-β1, 2, 3) and TGFβ receptors (TGFBR1, 2, 3) wa...

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Detalles Bibliográficos
Autores principales: Zhang, Yan, Raychaudhuri, Suravi, Wildsoet, Christine F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4877072/
https://www.ncbi.nlm.nih.gov/pubmed/27214233
http://dx.doi.org/10.1371/journal.pone.0155356